Spectinomycin modification. II. Spectinomycin C-3'-modification via diazoketone intermediates.
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منابع مشابه
Spectinomycin modification. II. Spectinomycin C-3'-modification via diazoketone intermediates.
The C-3'-carbonyl group of N-protected spectinomycin is efficiently converted into a diazo group via base treatment of the corresponding tosylhydrazone. The diazo group imparts a new synthetically useful reactivity pattern on the sugar ring of the molecule. The synthesis of C-3'-deoxo-, monohalo- and dihalospectinomycins via the intermediacy of these diazo compounds is described. The reduced bi...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1985
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.38.197